The design of the instrument is such that the sample is always at ground potential and in a horizontal orientation. All components such as ion guns, analyser, secondary electron detector, electron flood gun and video cameras are aligned to the joint point of analysis. This allows permanent control of the analysed area and excellent sample navigation.

Rapid location of the area of interest on the sample can be made by using the two TV cameras. In addition, higher resolution total ion or electron images of the sample for area location and topographical information can be acquired.

If necessary, the sample holder may be scanned prior to analysis on a high resolution computer scanner, and the digital image can be transmitted to the TOF.SIMS 5 navigation software.